New derivatives of progesterone were synthesized by the reaction of
progesterone with hydrazine and thiosemicarbazide then cyclized by using of
ethylacetoacetate and ethylallylmalonate.
The new compounds were characterized
by using of Melting point and FT-IR spectroscopy.
The new compounds were
tested against selected types of gram positive and gram negative bacteria,and show
encarge activity.
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